Grégory Chagnon Homepage.
About Me
My work focuses on the mechanical behaviour of materials during large deformations and mainly concerns soft biological tissues, bioresorbable polymers and elastomeric materials. My research focuses on experimental characterisation and the development of constitutive equations. My work concerns materials of and for the living, with the aim of developing medical devices or understanding pathologies. .
Positions
Degrees
Research Interests
Publications
For my citation indices, see Google Scholar, ORCID or Web of Science
For my Research Gate profile
Thesis
[3] Chagnon Grégory
Contribution to the study of architectured materials in large deformations for biomedical applications
Habilitation thesis, University of Grenoble, France (2011).
[2] Chagnon Grégory
Modelling of Mullins effect in rubber like materials
PhD thesis, Ecole Centrale de Nantes, France (2003).
[1] Chagnon Grégory
Modelling of damage in rubber like materials
Master thesis, Ecole Centrale de Nantes, France (2000).
Articles in peer-reviewed journals
[71] Durcan, C., Hossain, M., Chagnon, G., Peric, D., Girard, E. (2024).
Characterisation of the layer, direction and time-dependent mechanical behaviour of the human oesophagus and the effects of formalin preservation.
J. R. Soc. Interface, accepted.
doi link not active
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[70] Duraes, M., Briot, N., Connesson N., Chagnon, G., Payan, Y., Duflos, C., Rathat G., Captier, G., Subsol, G., Herlin, C. (2024).
Evaluation of breast skin and tissue stiffness using a noninvasive aspiration device and impact of clinical predictors.
Clinical Anatomy, 1-8.
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[69] Durcan, C., Hossain, M., Chagnon, G., Peric, D., Girard, E. (2023).
Mechanical experimentation of the gastrointestinal tract: a systematic review.
Biomechanics and Modeling in Mechanobiology, 23, 23–59.
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[68] Chagnon, G., Durcan, C., Hossain, M., Peric, D., Girard, E. (2023).
Experimental study of the different layers of the human oesophagus.
Computer Methods in Biomechanics and Biomedical Engineering, S51-S53.
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[67] Picard, M.-C., Cotton, M., Briot, N., Nazari, M.-A., Poisbleau, D., Perrier, P., Chagnon, G., Rochette, M., Payan, Y. (2023).
Biomechanical model of the human face with a perspective of surgical assistance.
Computer Methods in Biomechanics and Biomedical Engineering, S202-S204.
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[66] Fougeron, N., Trebbi, A., Keenan, B., Payan, Y., Chagnon, G..(2023).
Current Poisson’s ratio values of finite element models are too low to consider soft tissues nearly-incompressible: illustration on the human heel region.
Computer Methods in Biomechanics and Biomedical Engineering, 1-10.
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[65] Liao, Z., Yiang, J., Hossain, M., Chagnon, G., Yao, X., (2023).
The time and temperature dependences of the stress recovery of Ecoflex polymer.
International Journal of Non-Linear Mechanics, 149, 104338.
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[64] Fougeron, N., Rivals, I., Connesson, N., Chagnon, G., Alonso, T., Pasquinet, L., Auguste, S., Perrier, A., Payan, Y.(2022).
Pressure ulcers and dressings: a strain sensitivity analysis of the boundary conditions of a finite element model.
Biomechanics, 3(1), 1-12.
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[63] Grosjean, M., Girard, E., Bethry, A., Chagnon, G., Garic, X., Nottelet, B. (2022).
Radiopaque PolyDegradable bioadhesives based on star PEG-PLA hydrogels for soft tissue applications.
Biomacromolecules, 24, 4430-443.
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[62] Fougeron, N., Connesson, N., Chagnon, G., Alonso, T., Pasquinet, L., Bahuon, M., Guillin, E., Perrier, A., Payan, Y. (2022).
Modelling quasi-incompressibility of soft-tissues to quantify strains for pressure ulcers healing.
Computer Methods in Biomechanics and Biomedical Engineering.
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[61] Briot, N., Chagnon, G., Connesson, N., Payan, Y. (2022).
In vivo measurement of breast tissues stiffness using a light aspiration device.
Clinical Biomechanics. 99 105743.
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[60] Durcan, C., Hossain, M., Chagnon, G., Peric, D., Bsiesy, L., Karam, G., Girard, E. (2022).
Experimental investigations of the human oesophagus: anisotropic properties of the embalmed mucosa–submucosa layer under large deformation.
Biomechanics and Modeling in Mechanobiology, 21.
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[59] Fougeron, N., Connesson, N., Chagnon, G., Alonso, T., Pasquinet, L., Bahuon, M., Guillin, E., Perrier, A., Payan, Y.(2022).
New dressings design for pressure ulcers to alleviate human soft tissues : a finite element study.
Journal of Tissue Viability, 31, 506-513.
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[58] Durcan, C., Hossain, M., Chagnon, G., Peric, D., Bsiesy, L., Karam, G., Girard, E. (2022).
Experimental investigations of the human oesophagus : mechanical characterisation of the embalmed muscular layer.
Biomechanics and Modeling in Mechanobiology, 21, 1169–1186.
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[57] Briot, N., Chagnon, G., Burlet, L., Gil, H., Girard, E., Payan, Y. (2022).
Experimental characterization and modelling of breast Cooper Ligaments.
Biomechanics and Modeling in Mechanobiology, 21, 1157–1168.
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[56] Chagnon, G., Achouri, K., Connesson, N., Gerbelot, J., Courvoisier, A. (2021).
Development and operation of an experimental system to measure the moments generated in the finger joints.
Bioengineering, 9, 184.
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[55] Liao, Z., Yang, J., Hossain, M., Chagnon, G., Jing, L., Yai, X. (2021).
On the stress recovery behaviour of Ecoflex silicone rubbers.
International Journal of Mechanical Sciences, 206, 106624.
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[54] Manifacier, I., Chauviere, A., Verdier, C., Chagnon, G., Cheddadi, I., Glade, N., Stephanou, A. (2020).
A minimal biomechanical model for random cell migration..
Computer Methods in Biomechanics and Biomedical Engineering, 23, S183-S185.
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[53] Briot, N., Chagnon, G., Masri, C., Girard, E., Payan, Y. (2020).
Ex-vivo mechanical characterisation of the breast cooper's ligaments.
Computer Methods in Biomechanics and Biomedical Engineering, 23, S49-S51.
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[52] Girard, E., Chagnon, G., Moreau-Gaudry, A., Letoublon, C., Favier, D., Dejean, S., Trilling, B., Nottelet, B. (2020).
Evaluation of a biodegradable PLA-PEG-PLA internal biliary stent for liver transplantation : in vitro degradation and mechanical properties.
Journal of Biomedical Materials Research, 109, 410-419.
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[51] Grassi, E., Chagnon, G., Ramos de Oliveira, H., Favier D. (2020).
Anisotropy and Clausius-Clapeyron relation for forward and reverse stressinduced martensitic transformations in polycrystalline NiTi thin walled tubes.
Mechanics of Materials, 146, 103392.
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[50] Liao, Z., Hossain, M., Yao, X., Navaratne, R., Chagnon, G.. (2020).
A comprehensive thermo-viscoelastic experimental investigation of Ecoflex polymer.
Polymer Testing, 86, 106478.
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[49] Girard, E., Chagnon, G., Broisat, A., Dejean, S., Soubies, A., Gil, H., Sharkawi, T., Boucher, F., Roth, G.S., Trilling, B., Nottelet, B. (2020).
From in vitro evaluation to human postmortem pre-validation of a radiopaque and resorbable internal biliary stent for liver transplantation applications.
Acta Biomaterialia, 209, 109948.
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[48] Tan, C.J., Bee Chin, A., Andriyana, A., Chagnon, G. (2020).
Biostable Highly Aligned Polyurethane Fibres for the Potential Application of Small Calibre Vascular Grafting.
Materials Science and Engineering Technology, 51, 1473-1480
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[47] Schaefer, P.L., Chagnon, G., Moreau Gaudry, A. (2020).
3D large displacement beam shape sensing including poisson effect.
Engineering Structures, 209, 109948.
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[46] Achouri, K., Connesson, N., Chagnon, G., Gerbelot, J., Courvoisier, A. (2019).
Experimental evaluation of the forefinger maximum bending moments.
Computer Methods in Biomechanics and Biomedical Engineering, 22:sup1, S334-S335.
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[45] Gagnieu, A., Chagnon, G., Chemisky, Y., Stephanou, A., Chauvière, A. (2019).
On the importance of substrate deformations for cell migration.
Computer Methods in Biomechanics and Biomedical Engineering, 22:sup1, S334-S335.
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[44] Alonso, T., Chagnon, G., Favier, D. (2019).
Characterizing transformation phenomena and elastic moduli of austenite and oriented martensite of superelastic Thin NiTi wire through isothermal dynamic mechanical analysis.
Journal of Materials Engineering and Performance, 28, 4667.
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[43] Girard, E., Chagnon, G., Gremen, E., Calvez, M., Masri, C., Boutonnat, J., Trilling, B., Nottelet, B. (2019).
Biomechanical behaviour of human bile duct wall and impact of cadaveric preservation processes.
Journal of the Mechanical Behavior of Biomedical Materials, 98, 291-300.
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[42] Schaefer, P.L., Chagnon, G., Moreau-Gaudry, A. (2019).
Strain Gauges Based 3D Shape Monitoring of Beam Structures Using Finite Width Gauge Model .
Experimental Techniques, 57, 1901-1916.
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[41] Tan, C.J., Lee, J.L.L., Bee Chin, A., Andriyana, A., Chin, A.B., Chagnon, G., Sukiman, M. S. (2019).
Design of Polyurethane Fibers: Relation between theSpinning Technique and the Resulting Fiber Topology.
Journal of Applied Polymer Science, 136, 47706
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[40] Schaefer, P.L., Barrier, G., Chagnon, G., Alonso, T., Moreau-Gaudry, A. (2019).
Strain Gauges Based 3D Shape Monitoring of Beam Structures Using Finite Width Gauge Model .
Experimental Techniques
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[39] Elahi, S.A., Connesson, N., Chagnon, G., Payan, Y. (2019).
In-Vivo Soft Tissues Mechanical Characterization: Volume-Based Aspiration Method Validated on Silicones.
Experimental Mechanics, 59(251)
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[38] Tan, C.J., Andriyana, A., Chin, A.B., Chagnon, G. (2018).
Inelastic deformation of highly aligned dry-spun thermoplastic polyurethane elastomer microfibres.
Materials Research Express, 5 (12), 125301
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[37] Dalla Monta, A., Razan, F., Le Cam, J.B., Chagnon, G. (2018).
Using thickness-shear mode quartz resonator for characterizing the viscoelastic properties of PDMS during cross-linking, from the liquid to the solid state and at different temperatures.
Sensors and Actuators, A Physical, 280, 107-113
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[36] Masri, C., Chagnon, G., Favier, D., Sartelet, H., Girard, E. (2018).
Experimental characterization and constitutive modeling of the biomechanical behavior of male human urethral tissues validated by histological observations.
Biomechanics and Modeling in mechanobiology, 17, 939
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[35] Masri, C., Chagnon, G., Favier, D. (2017).
Influence of processing parameters on the macroscopic mechanical behavior of PVA hydrogels.
Materials Science and Engineering C, 75, 769-776
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[34] Machado, G., Stricher, A., Chagnon, G., Favier, D. (2017).
Mechanical behavior of architectured photosensitive silicone membranes: experimental data and numerical analysis.
Mechanics of Advanced Materials and Structures, 24, 524-533
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[33] Rebouah, M., Chagnon, G., Heuillet, P. (2017).
Anisotropic viscoelastic models in large deformation for architectured membranes.
Mechanics of Time-Dependent Materials, 21(2), 163-176.
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[32] Breche, Q., Chagnon, G., Machado, G., Nottelet, B., Garric, X., Girard, E., Favier, D. (2016).
A non-linear viscoelastic model to describe the mechanical behavior's evolution of biodegradable polymers during hydrolytic degradation.
Polymer Degradation and Stability, 131, 145-156.
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[31] Stricher, A., Rinaldi, R. G., Machado, G., Chagnon, G., Favier, D., Chazeau L., Ganachaud, F. (2016).
Light-Induced Bulk Architecturation of PDMS Membranes.
Macromolecular Materials and Engineering, 301, 1151-1157
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[30] Marckmann, G., Chagnon, G., Le Saux, M., Charrier, P. (2016).
Experimental investigation and theoretical modelling of induced anisotropy during stress-softening of rubber.
International Journal of Solids and Structures, 97-98, 554-565.
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[29] Breche, Q., Chagnon, G., Machado, G., Girard, E., Nottelet, B., Garric, X., Favier, D. (2016).
Mechanical behaviour's evolution of a PLA-b-PEG-b-PLA triblock copolymer during hydrolytic degradation.
Journal of the Mechanical Behavior of Biomedical Materials, 60, 288-300.
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[28] Delobelle, V., Chagnon, G., Favier, D., Alonso, T. (2015).
Study of electropulse heat treatment of cold worked NiTi wire: from uniform to localised tensile behaviour.
Journal of Materials Processing Technology, 227, 244-250.
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[27] Samuel, R., Girard, E., Chagnon, G., Dejean, S., Favier, D., Coudane, J., Nottelet, B. (2015).
Radiopaque Poly(ε-caprolactone) as Additive for X-Ray Imaging of Temporary Implantable Medical Devices.
Royal Society of Chemistry Advances, 5, 84125.
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[26] Andriyana, A., Loo, M.-S., Chagnon, G., Verron, E., Ch'ng S.-Y. (2015).
Modeling the Mullins effect in elastomers swollen by palm biodiesel.
International Journal of Engineering Science, 95, 1-22.
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[25] Chagnon, G., Rebouah, M., Favier, D. (2015).
Hyperelastic energy densities for soft biological tissues: a review.
Journal of Elasticity, 120, 129-160.
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[24] Meunier, L., Chagnon G., Favier, D., Orgéas, L.,(2015).
Anisotropic large deformation of geometrically architectured unfilled silicone membranes.
European Journal of Mechanics - A/Solids, 50, 87-99.
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[23] Rebouah, M., Chagnon, G., Favier, D. (2015).
Development and modelling of filled silicone architectured membranes.
Meccanica, 50, 11-24.
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[22] Rey, T., Le Cam, J.-B., Chagnon, G., Favier, D., Rebouah, M., Razan, F., Robin, E., Didier, P., Heller, L., Faure, S. and Janouchova, K. (2014)
An original architectured NiTi silicone rubber structure for biomedical applications.
Materials Science and Engineering C, 45, 184-190.
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[21] Rey, T., Chagnon, G., Favier, D., and Le Cam, J.-B. (2014)
Hyperelasticity with rate-independent microsphere hysteresis model for rubberlike materials.
Computational Materials Science, 90, 89-98.
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[20] Rebouah, M., Chagnon, G. (2014).
Extension of classical viscoelastic models in large deformation to anisotropy and stress softening.
International Journal of non-linear mechanics, 61, 54-64.
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[19] Rebouah, M., Chagnon, G. (2014).
Permanent set and stress softening constitutive equation applied to rubber like materials and soft tissues.
Acta Mechanica, 225, 1685-1698.
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[18] Machado G., Chagnon G., and Favier D. (2014)
Theory and identification of a constitutive model of induced anisotropy by the Mullins effect.
Journal of the Mechanics and Physics of Solids, 63, 29-39
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[17] Linardon, C., Favier, D., Chagnon, G., Gruez, B. (2014).
A conical mandrel tube drawing test designed to assess failure criteria.
Journal of Materials Processing Technology, 214, 447-357
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[16] Rey, T., Razan, F., Robin, E., Faure, S., Le Cam, J.-B., Chagnon, G., Girard, A., and Favier, D. (2014).
Mechanical characterization and comparison of different NiTi/silicone rubber interfaces.
International Journal of Adhesion and Adhesives, 48, 67-74
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[15] Robert, A., Chagnon, G., Cinquin P. and Moreau-Gaudry, A. (2013).
Using a 3D needle-tissue force distribution basis to optimise the design of an instrumented needle.
Computer Methods in Biomechanics and Biomedical Engineering, 16, 320-322
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[14] Robert, A., Chagnon, G., Bricault I., Cinquin P. and Moreau-Gaudry, A. (2013).
A generic three-dimensional loading basis applied to a surgical needle inserted into a complex tissue.
Journal of the Mechanical Behavior of Biomedical Materials, 28, 156-170
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[13] Rebouah, M., Machado, G., Chagnon, G., Favier, D. (2013).
Anisotropic Mullins stress softening of a deformed silicone holey plate.
Mechanics Research Communications, 49(1), 36-43
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[12] Palengat, M., Chagnon, G., Favier, D., Louche, H., and Plaideau, C. (2013).
Cold drawing of 316L stainless steel thin-walled tubes: Experiments and finite element analysis.
International Journal of Mechanical Sciences, 70, 69-78
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[11] Rey, T., Chagnon, G., Le Cam, J.-B., and Favier, D. (2013).
Influence of the temperature on the mechanical behavior of two silicone rubbers above crystallization temperature.
Polymer Testing, 32, 492-501
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[10] Chagnon, G., Gaudin, V., Favier, D., Orgéas, L., and Cinquin, P. (2012).
An osmotically inflatable seal to treat endoleaks of type 1, following endovascular aneurysm repair.
Journal of Mechanics in Medicine and Biology, 12
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[9] Machado, G., Chagnon, G., and Favier, D. (2012).
Induced anisotropy by the Mullins effect in filled silicone rubber.
Mechanics of Materials, 50(1), 70-80
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[8] Machado, G., Favier, D., and Chagnon, G. (2012).
Membrane Curvatures and Stress-strain Full Fields of Axisymmetric Bulge Tests from 3D-DIC Measurements.
Theory and Validation on Virtual and Experimental results.
Experimental Mechanics, 52(7), 865-880
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[7] Toungara, M., Chagnon, G., and Geindreau, C. (2012).
Numerical analysis of the wall stress in abdominal aortic aneurysm: influence of the material model nearly-incompressibility.
Journal of Mechanics in Medicine and Biology, 12
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[6] Machado, G.,Chagnon, G., and Favier D. (2010).
Analysis of the isotropic models of the Mullins effect based on filled silicone rubber experimental results.
Mechanics of Materials, 42(9), 841-851
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[5] Meunier, L., Chagnon G., Favier, D., Orgéas, L., and Vacher, P. (2008).
Mechanical experimental characterisation and numerical modelling of an unfilled silicone rubber.
Polymer Testing, 29, 765-777
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[4] Chagnon G., Verron, E., Marckmann, G. and Gornet, L. (2006).
Development of new constitutive equations for mullins effect in rubber using the network alteration theory.
International Journal of Solids and Structures, 43, 6817-6831
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[3] Chagnon G., Verron, E., Gornet, L., Marckmann, G. and Charrier, P. (2004).
On the relevance of continuum damage mechanics as applied to the Mullins effect: theory, experiments and numerical implementation.
Journal of the Mechanics and Physics of Solids, 52, 1627-1650
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[2] Chagnon G., Marckmann, G. and Verron, E. (2004).
A comparison of the physical model of Arruda-Boyce with the empirical Hart-Smith model and the Gent model.
Rubber Chemistry and Technology, 77, 724-735
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[1] Marckmann, G., Verron, E., Gornet, L., Chagnon G., Charrier, P. and Fort, P. (2002).
A theory of network alteration for the Mullins effect.
Journal of the Mechanics and Physics of Solids, 50, 2011-2028
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Patent
[1] Favier, D., Alonso, T., Chagnon, G., Liu, Y., and Moreau-Gaudry, A. (2011)
Aiguille médicale à trajectoire modifiable et pieu pilote à rigidités multiples réalisées par traitement thermique local.
FR 1159387.
Chapter in Book
[2] Chagnon, G., Ohayon, J., Martiel, J.-L., Favier, D. (2017)
Hyperelasticity modeling for incompressible passive biological tissues.
in Biomechanics of Living Organs, Yohan Payan and Jacques Ohayon editors, Springer-Verlag.
HAL
[1] Luboz, V., Promayon, E., Chagnon, G., Alonso, T., Favier, D., Barthod, C. et Payan, Y. (2012)
Validation of a Light Aspiration device for in vivo Soft Tissue Characterization (LASTIC).
in Soft Tissue Biomechanical Modeling for Computer Assisted Surgery, Yohan Payan editor, Springer-Verlag.
HAL
Conference list
Visit HAL
PhD Students
[18] Ciara Durcan (2023)
Ex vivo experimental investigations and modelling of the layer-dependent, anisotropic, visco-hyperelastic behaviour of the human oesophagus.
University of Grenoble Alpes and University of Swansea.
PhD Supervisor with Mokarram Hossain
pdf
[17] Antoine Désigaux (2023)
Development as well as mechanical and structural characterization of an anisotropic elastomer reinforced by cellulose microfibrils.
University of Grenoble Alpes.
PhD Supervisor with Sonia Molina-Boisseau and Laurent Heux
pdf
[16] Noémie Briot (2022)
Ex vivo and in vivo characterisation of biological soft tissues for the biomechanical modelling of human breast.
University of Grenoble Alpes.
PhD Supervisor with Yohan Payan
pdf
[15] Khouloud Achouri (2021)
Développement de dispositifs de mesures biomécaniques pour l'aide à la conception des orthèeses articulaires patient-spécifque.
University of Grenoble Alpes.
PhD Supervisor with Aurélien Courvoisier
pdf
[14] Chin Joo Tan (2020)
Fabrication and characterization of highly aligned thermoplastic polyurethane fibrous assemblies.
University of Malaya.
PhD Supervisor with Andri Andriyana and Ang Bee Chin
pdf
[13] Edouard Girard (2018)
Development of a bilary resorbable prosthesis to secure bilary anastomosis in liver transplant.
University of Grenoble Alpes.
PhD Supervisor with Benjamin Nottelet
pdf
[12] Estephanie Grassi (2018)
Anisotropic behaviour of thin walled medical tubes in Nickel-Titanium superelastic shape memory alloys.
University of Grenoble Alpes.
PhD Supervisor with Denis Favier
pdf
[11] Masri Christopher (2017)
Study of an occlusive cuff for a smat artificial urinary sphincter.
University of Grenoble Alpes.
PhD Supervisor with Denis Favier Confidential.
[10] Schaefer Pierre-Loup (2017)
Reconstruction de la déformée d'une aiguille instrumentée.
University of Grenoble Alpes.
PhD Supervisor with Philippe Cinquin and Alexandre Moreau-Gaudry
pdf
[9] Brèche Quentin (2016)
Copolymères triblocs biodégradables PLA-b-PEG-b-PLA pour ingénierie tissulaire. Caractérisation et modélisation de l’évolution de leurs propriétés mécaniques au cours de leur dégradation par hydrolyse.
University of Grenoble Alpes.
PhD Supervisor with Denis Favier
pdf
[8] Alonso Thierry (2015)
Characterization by DMA test and thermomechanical behaviour optimization of NiTi wires - Application to a medical steerable needle.
University of Grenoble Alpes.
PhD Supervisor with Denis Favier
pdf
[7] Rebouah Marie (2014)
Anisotropic stress softening and viscoelasticity in rubber like materials and architectured materials
University of Grenoble.
pdf
[6] Rey Thierry (2014)
Contribution to the elaboration, experimentation shape memory alloy Nickel-Titanium/silicone rubber composites
University of Grenoble.
PhD Supervisor with Denis Favier and Jean-Benoit Le Cam
pdf
[5] Robert Adeline (2013)
Navigation d'une aiguille médicale déformable
University of Grenoble.
PhD Supervisor with Philippe Cinquin and Alexandre Moreau-Gaudry
pdf (in French)
[4] Linardon Camille (2013)
Étirage de tubes de précision pour applications biomédicales. Contribution à l'analyse et l'amélioration du procédé par expérimentation, modélisation et simulation numérique
University of Grenoble.
PhD Supervisor with Denis Favier
pdf
[3] Machado Guilherme (2011)
A contribution to the study of induced anisotropy by Mullins effect in silicone rubber
University of Grenoble.
PhD Supervisor with Denis Favier
pdf
[2] Palengat Muriel (2009)
Modélisation des couplages multiphysiques matériaux-produits-procédés lors de l'étirage de tubes : applications aux alliages métalliques usuels
University of Grenoble - Collaboration Minitubes SA.
PhD Supervisor with Denis Favier
pdf
[1] Meunier Luc (2008)
Contribution à la conception, l’expérimentation et la modélisation de membranes hyperélastiques architecturées anisotropes
University of Grenoble.
PhD Supervisor with Denis Favier
Some Projects
ANR - RAMMO (Eel-Like Robot with electric sense) 2007-2011
This ANR Project aiming at the design, construction and control of a 3D eel-like robot with electrical sensing that is usually used by the electric fishes.
The robot is composed of 12 vertebras connected through a rotation free joints. The whole robot is covered with a skin that is especially designed
in order to avoid perforation due to the water pressure while allowing an easy swimming oriented ondulations. Our team role in this project is to design this skin,
composed by a special silicone rubber material.
Leader: F. Boyer
Partners: IRCCyN (Nantes)/ GIPSA-LAB (Grenoble) / LMF (Nantes) / SUBATECH (Nantes) / UNIC (Paris)
ANR - ANiM (Architectured Ni-Ti Materials) 2010-2014
This project aims to develop a new category of innovative materials combining the intrinsic and novel properties of
Nickel-Titanium shape memory alloys with purposely engineered topologies allowed by the notion of “architectured materials”. More specifically,
we aim to create architectured materials constituted of NiTi wires and tubes. Using fibres cut from thin wires, we will create non-woven random
2D textiles, 3D blocks of low solid densities, and more complex designed architectures. With thin-wall tubes we will create regular cellular
materials. To realise these unique structures we apply a range of innovative materials processing techniques, such as plasma sintering,
electric resistance welding, diffusion brazing, and silicone elastomer infiltration.
Our team role is to study and improve the interface between NiTi and silicone rubber.
Leader: D. Favier
Partners: LMGC (Montpellier) / SIMAP (Grenoble) / LARMUR (Rennes) / LIMATB (Lorient) / 3SR (Grenoble)
ANR - SAMBA (Silicone Architectured Membranes for Biomedical Applications) 2012-2016
This project takes its source in an array of works aiming at designing highly deformable anisotropic membranes for medical applications.
The silicone rubbers are highly deformable biomaterials widely used by surgeons for their mechanical properties controlled by their crosslinking rate.
In current medical applications, the properties of silicones are homogeneous and isotropic.
In the present biomimetic approach, our researches aim to provide the clinician elastomeric membranes whose local properties can possibly be non-uniform and will be fully controlled during their elaboration, both in rigidity and anisotropy.
Leader: G. Chagnon
Partners: IMP (Lyon)/ MATEIS (Lyon)
ANR - BioScaff (Hyperelastic and absorbable architected materials dedicated to soft tissue reconstruction) 2016-2020
This multidisciplinary project is part of the development of new cell growth supports or "scaffolds" dedicated to soft tissue regeneration. In order to optimize the development of new implantable medical devices, the objective of the project is to set up and validate a methodology for predicting the evolution of the mechanical properties of biocomposite "growing scaffold / tissue tissue" during antagonistic effects. Biodegradation of scaffold and its colonization by the biological tissue. For this purpose, new bioresorbable and biocompatible block polymers with hyperelastic behaviour close to soft tissues will be synthesized. These materials will be shaped by electrospinning to produce biomimetic supports promoting cell growth. The mechanical properties of its supports will be characterized in the presence of growing cells at different stages of degradation. Numerical simulation methods, from the cell scale to the support, will integrate the experimental results obtained to characterize and ultimately predict the mechanical behaviour supports based on these intrinsic properties.
Leader: F. Bossard
Partners: LRP (Grenoble) / IBMM (Montpellier)
Contact
phone: +33 (0)4 56 52 00 86
fax: +33 (0)4 76 76 88 44
email: gregory [dot] chagnon [at] univ-grenoble-alpes [dot] fr
Address:
Laboratoire TIMC - Bioméca Team
Pavillon TAILLEFER
IN3S INstitut de l'INgénierie et de l'INformation de Santé
38706 LA TRONCHE CEDEX - FRANCE
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